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Consequently, interventions designed to restore NO bioavailability, enhance mitochondrial functionality, and improve microvascular perfusion represent promising therapeutic strategies to mitigate age-related muscular degeneration and sustain physical performance in the elderly population

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POMC neurons and AgRP neurons in the arcuate extend dendrites that physically project into the median eminence to sample circulating hormones, glucose, and now, evidently, large peptide drug conjugates

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